Failure of Natalizumab to Prevent Relapses in Neuromyelitis Optica
نویسندگان
چکیده
منابع مشابه
Failure of natalizumab to prevent relapses in neuromyelitis optica.
OBJECTIVE To describe first experiences with the integrin inhibitor natalizumab, given to patients with suspected relapsing-remitting multiple sclerosis (MS) who were later diagnosed with aquaporin 4-positive neuromyelitis optica (NMO). DESIGN Retrospective case series. SETTING Neurology departments at tertiary referral centers in Germany. PATIENTS Patients with NMO who tested positive fo...
متن کاملNeuromyelitis optica presenting with relapses under treatment with natalizumab: a case report
INTRODUCTION Neuromyelitis optica is an inflammatory demyelinating disease of the central nervous system. To date, optimal therapeutic approaches for neuromyelitis optica have yet to be defined. Natalizumab is highly effective in relapsing-remitting multiple sclerosis and might be considered as an option. CASE PRESENTATION Here, we describe a 67-year-old Caucasian man with definite neuromyeli...
متن کاملSeasonality of 278 neuromyelitis optica relapses in a Brazilian cohort.
Bichuetti DB has received speaking honoraria from Bayer Health Care, Merck Serono and Biogen Idec, serves in advisory board meetings by Merck Serono and Sanofi Genzyme and had travel expenses to scientific meetings paid by Bayer Health Care, Merck Serono and TEVA. Souza NA had travel expenses to scientific meetings paid by Bayer Health Care, Merck Serono and TEVA. Oliveira EML received compensa...
متن کاملFailure of autologous hematopoietic stem cell transplantation to prevent relapse of neuromyelitis optica.
H ere we describe a woman with relapsing neuromyelitis optica (NMO) who was seropositive for NMO-IgG and who experienced a relapse of myelitis 4 months after autologous hematopoietic stem cell transplantation (AHSCT) for a lymphoma that developed while receiving azathioprine therapy. Analysis of serum samples obtained at key points in her disease course using 3 different serological techniques ...
متن کاملNeuromyelitis Optica in Children: A Rare Entity
Neuromyelitis optica (also known as Devic's disease or Devic's syndrome) is an uncommon disorder in pediatric age group, and is characterized by acute or subacute optic neuritis and transverse myelitis. Here we report an 11- year- old female child with relapsing Neuromyelitis optica (NMO) confirmed by positive NMO- IgG antibody and had clinical recovery with high dose methyl prednisolone t...
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ژورنال
عنوان ژورنال: Archives of Neurology
سال: 2012
ISSN: 0003-9942
DOI: 10.1001/archneurol.2011.216